These actors guest-starred on the medical drama before making a name for themselves.
Most are one-off hospital patient roles, but some recurring medical professionals on the show should be instantly recognizable.
Chandlers character famouslydid not survive his time on the show.
Millie Bobby Brown, Leslie Odom Jr., and Sarah Paulson on ‘Grey’s Anatomy’.Credit:ABC (3)
The future Tony winner/Oscar nominee played P.J.
Walling, who joined a domino kidney transplant to help his ailing father.
Siff portrayed Ruthie, a young woman admitted to the hospital with a crushed ankle.
Tessa Thompson and Kate Walsh on ‘Grey’s Anatomy’.Gale Adler/ABC via Getty Images
Tests revealed she had early osteoporosis stemming from extreme dieting, leading to a surgery she did not survive.
She stayed in theShondalandfamily when she took on the role of Quinn Perkins onScandalthe very next year.
She appeared as Kathy, a woman who has sustained multiple athletics-related injuries.
Sandra Oh, Isaiah Washington, and Kyle Chandler on ‘Grey’s Anatomy’.Peter ‘Hopper’ Stone/ABC
Dylan Minnette
Yes, this isthatDylan Minnette.
The13 Reasons Whystar showed up onGrey’sin the season 4 episode “Haunt You Every Day” in 2007.
Minnette played Ryan, a boy with no external ear despite being able to hear.
Leslie Odom Jr. on ‘Grey’s Anatomy’.ABC
After complications with insurance, she finally had surgery that greatly improved her symptoms.
But it’s now impossible to separate him from Hank Schrader onBreaking Bad, which premiered a year later.
Billings played Donna, a trans woman hoping for a vaginoplasty to further her transition.
Elisabeth Moss on ‘Grey’s Anatomy’.ABC
Jesse Plemons on ‘Grey’s Anatomy’.ABC
Maggie Siff on ‘Grey’s Anatomy’.ABC
Katie Lowes on ‘Grey’s Anatomy’.ABC
Bellamy Young on ‘Grey’s Anatomy’.ABC
Dylan Minnette on ‘Grey’s Anatomy’.ABC
Millie Bobby Brown and Kevin McKidd on ‘Grey’s Anatomy’.ABC
Judith Hoag, Mae Whitman, and Chandra Wilson on ‘Grey’s Anatomy’.Michael Desmond/ABC
Dean Norris on ‘Grey’s Anatomy’.ABC
Alexandra Billings on ‘Grey’s Anatomy’.ABC
Jamie Chung on ‘Grey’s Anatomy’.ABC
Michaela Watkins on ‘Grey’s Anatomy’.ABC
Sarah Paulson on ‘Grey’s Anatomy’.ABC
