“Nobody wanted to work with me.

And I understood why, and I took responsibility for myself, but it was a great lesson.”

“To always be grateful,” she replied on Wednesday’s episode ofThe Drew Barrymore Show.

Drew Barrymore at the Youth in Film Awards at the Various Locations in Universal City, California; Drew Barrymore on The Drew Barrymore Show

A young Drew Barrymore; Barrymore on ‘The Drew Barrymore Show’.Credit:Barry King/WireImage; The Drew Barrymore Show

From my own doing."

And I understood why, and I took responsibility for myself, but it was a great lesson."

It was a really rebellious time.

Drew Barrymore poses for a photograph in 1982 in New York City

Drew Barrymore poses for a photograph in 1982 in New York City.Yvonne Hemsey/Getty

I would run off.

I was very, very angry."

As a result, she said, she feels lucky for each new opportunity that comes her way.

The Drew Barrymore Show Drew Barrymore, Valerie Bertinelli and Steven Spielberg at the 52nd Annual Academy Awards - Rehearsals in 1980

“And so it also told me not to regret.

What good is that gonna do?

Our mistakes are our best teachers.”

Drew Barrymore furiously digs through dirt to win talk show audience member a luxury vacation

The Drew Barrymore Showairs weekdays on CBS.

Drew Barrymore on The Drew Barrymore Show

Drew Barrymore on ‘The Drew Barrymore Show’.The Drew Barrymore Show