The rappers have recorded over a dozen songs together over the last two decades.

Leon Bennett/Getty

Eminemhas offered his two cents on a potential collaboration album with another legendary rapper.

“That would be great,” Eminem opined.

Curtis “50 Cent” Jackson and Eminem pose during a ceremony honoring 50 Cent with a star on the Hollywood Walk of Fame on January 30, 2020

50 Cent and Eminem at 50 Cent’s Hollywood Walk of Fame ceremony in 2020.Credit:Leon Bennett/Getty

He added, “I would never say it’s not possible, s—!”

The duo’s collaborations aren’t just relegated to the recording booth and the stage, either.

“It was an honor to have him on the show and it made this episode extra special.”

Eminem attends the ceremony honoring Curtis “50 Cent” with a Star on the Hollywood Walk of Fame on January 30, 2020 in Hollywood, California.

Eminem at 50 Cent’s Hollywood Walk of Fame ceremony in 2020.Axelle/Bauer-Griffin/FilmMagic

“It’s gonna be big,” he teased.

“I’m down to fight Mike Tyson if he can’t hit me.”