The two actors play odd-couple cousins, who travel to Poland to honor their Holocaust survivor grandmother.

Together, they make for an all-time comedic odd-couple, with both actors showcasing their comedic and dramatic talents.

The introverted David holds his anxieties close to his chest.

Kieran Culkin and Jesse Eisenberg appear in A Real Pain by Jesse Eisenberg

Kieran Culkin and Jesse Eisenberg in ‘A Real Pain’.Courtesy of Sundance Institute